In clinical practice, few measurements provide as much insight into a person’s metabolic health as fasting blood glucose (FBG). Whether you’re monitoring diabetes, evaluating insulin sensitivity, or simply trying to optimize your long-term health, your fasting glucose number is a foundational indicator. But what exactly constitutes a “good” fasting glucose level? The answer, while seemingly straightforward, varies depending on age, health status, and individual metabolic conditions.
As a diabetes specialist, I often encounter patients confused about the nuances behind this number. They might read conflicting figures online or hear different opinions from various healthcare sources. In this article, I aim to clarify what a good fasting glucose level is, how it’s measured, why it matters, and what factors influence it.
What Is Fasting Blood Glucose?
Fasting blood glucose refers to the level of glucose (sugar) in the bloodstream after an individual has not eaten for at least 8 hours. This test is typically conducted first thing in the morning before any food or drink (except water) is consumed.
Glucose is the primary energy source for the body’s cells. It enters the bloodstream from the food we eat, especially carbohydrate-rich foods. The hormone insulin, produced by the pancreas, helps regulate the uptake of glucose into cells, thereby lowering its concentration in the blood.
When this regulatory system falters—due to insulin resistance, pancreatic dysfunction, or other issues—glucose can remain elevated in the bloodstream. Chronically elevated glucose levels are associated with prediabetes, type 2 diabetes, cardiovascular disease, and other complications.
What Are Normal, Prediabetic, and Diabetic Fasting Glucose Ranges?
Here are the widely accepted reference ranges for fasting blood glucose, based on guidelines from the American Diabetes Association (ADA):
Normal: 70–99 mg/dL (3.9–5.5 mmol/L)
Prediabetes (Impaired Fasting Glucose): 100–125 mg/dL (5.6–6.9 mmol/L)
Diabetes: 126 mg/dL (7.0 mmol/L) or higher on two separate occasions
It’s important to understand that a single elevated reading does not automatically indicate diabetes. Diagnosis requires either repeat testing or a combination of other clinical markers (such as HbA1c levels, oral glucose tolerance tests, and symptom presentation).
Is “Normal” Always “Optimal”? A Functional Medicine Perspective
While the conventional range of 70–99 mg/dL is deemed “normal,” many endocrinologists and integrative medicine practitioners believe that optimal fasting glucose lies closer to the middle of that spectrum, typically between 75–85 mg/dL.
This view is based on several large-scale observational studies that suggest individuals with fasting glucose levels above 90 mg/dL—although technically still within the normal range—may already show signs of insulin resistance and are at a higher risk for developing type 2 diabetes and cardiovascular disease in the future.
For example, research published in Diabetes Care has shown that individuals with fasting glucose in the high-normal range (95–99 mg/dL) had a significantly higher risk of developing diabetes than those with glucose levels below 85 mg/dL.
Therefore, when counseling patients, especially those with a family history of diabetes or metabolic syndrome, I advocate for proactive strategies to maintain fasting glucose below 90 mg/dL whenever possible.
The Physiology Behind Fasting Glucose Regulation
Fasting glucose is not influenced solely by diet. It’s the result of a complex interplay among several physiological systems:
1. Pancreatic Function
The pancreas must be able to sense blood glucose accurately and respond by releasing insulin. In early insulin resistance, the pancreas compensates by producing more insulin, which can maintain normal glucose levels for a while. Over time, this compensatory mechanism fails, and fasting glucose begins to rise.
2. Liver Activity
During fasting, the liver maintains glucose availability through a process called gluconeogenesis (production of glucose from non-carbohydrate sources). In insulin resistance, this process can become dysregulated, resulting in excessive glucose release even when it’s not needed.
3. Hormonal Regulation
Besides insulin, hormones such as cortisol (stress hormone), glucagon, and growth hormone also influence fasting glucose levels. Elevated cortisol, in particular, can drive up fasting glucose via hepatic glucose production, especially in chronically stressed individuals.
When Is a High Fasting Glucose Number Concerning?
A single elevated fasting glucose number (e.g., 110 mg/dL) does not always mean something is seriously wrong. Variations in fasting glucose can result from several transient factors:
-
Poor sleep the previous night
-
Elevated stress or cortisol levels
-
A late or high-carb meal before bedtime
-
Illness or infection
-
Certain medications (e.g., corticosteroids)
However, persistent readings in the prediabetic range (100–125 mg/dL) over several weeks warrant deeper evaluation. In these cases, a hemoglobin A1c test, continuous glucose monitoring (CGM), or an oral glucose tolerance test (OGTT) can provide more detailed insights into glucose metabolism.
Fasting Glucose vs. HbA1c vs. Postprandial Glucose
While fasting glucose provides a snapshot of blood sugar control at a specific moment, it’s only one piece of the puzzle. A more comprehensive picture includes:
Hemoglobin A1c: Reflects average blood glucose over the past 2–3 months. A normal A1c is below 5.7%, prediabetes is 5.7%–6.4%, and diabetes is 6.5% or higher.
Postprandial Glucose (PPG): Measures blood glucose 1–2 hours after eating. Ideally, this should remain below 140 mg/dL in non-diabetic individuals and below 180 mg/dL in those with diabetes.
Some patients have normal fasting glucose but elevated postprandial spikes. This is known as isolated postprandial hyperglycemia and may still reflect early metabolic dysfunction.
Who Should Regularly Monitor Fasting Glucose?
Frequent fasting glucose testing is especially important for individuals who fall into the following categories:
-
Family history of type 2 diabetes
-
Overweight or obesity (especially central adiposity)
-
Sedentary lifestyle
-
Polycystic ovary syndrome (PCOS)
-
History of gestational diabetes
-
Hypertension or dyslipidemia
-
Age over 45
-
History of cardiovascular disease
However, even individuals without these risk factors may benefit from occasional monitoring, especially if they are experimenting with dietary changes, weight loss, or lifestyle modifications.
What Affects Your Fasting Glucose?
There are multiple modifiable and non-modifiable factors that influence fasting blood glucose levels:
Modifiable Factors:
Diet: High-glycemic carbohydrates, late-night eating, and frequent snacking can all elevate fasting glucose over time.
Exercise: Regular physical activity increases insulin sensitivity and reduces fasting glucose.
Sleep: Poor sleep, especially due to sleep apnea or insomnia, is strongly linked to impaired glucose regulation.
Stress: Chronic psychological stress raises cortisol, which increases hepatic glucose production.
Alcohol: Excessive or poorly timed alcohol intake can impair liver function and disrupt glucose balance.
Medications: Certain drugs can either elevate or suppress fasting glucose.
Non-Modifiable Factors:
Genetics: Some individuals are genetically predisposed to insulin resistance.
Age: Insulin sensitivity tends to decline with age.
Hormonal Changes: Menopause, andropause, and thyroid dysfunctions can influence glucose regulation.
Interpreting Fasting Glucose with Context
Numbers must always be interpreted in the broader clinical context. For example:
A fit 30-year-old with a fasting glucose of 98 mg/dL may not be at risk, especially if other markers (like HbA1c and insulin) are normal.
A 60-year-old with a reading of 98 mg/dL and abdominal obesity, hypertension, and elevated triglycerides may already be experiencing metabolic syndrome.
As clinicians, we must avoid reductionism. Glucose levels are indicators—not final verdicts. Patterns and trends often reveal more than isolated values.
How to Improve Fasting Glucose Naturally
For patients looking to reduce fasting glucose levels without medication, these strategies often prove effective:
Prioritize Low-Glycemic Foods: Incorporate fiber-rich vegetables, lean protein, healthy fats, and slow-digesting carbohydrates.
Increase Physical Activity: Even brisk walking for 30 minutes daily improves insulin sensitivity.
Improve Sleep Hygiene: Aim for 7–8 hours of uninterrupted sleep each night.
Reduce Evening Carbs: Keeping dinners light and low in carbs helps curb overnight glucose production.
Manage Stress: Techniques such as meditation, breathing exercises, and mindfulness can reduce cortisol levels.
Time Your Meals: Intermittent fasting or early time-restricted feeding (e.g., finishing dinner by 6–7 pm) may improve fasting glucose in some individuals.
When Medication Is Necessary
If fasting glucose remains consistently above 125 mg/dL or if HbA1c crosses 6.5%, lifestyle changes alone may not be sufficient. Medications like metformin are often the first line of treatment for type 2 diabetes or prediabetes in higher-risk individuals. Other drug classes such as SGLT2 inhibitors or GLP-1 receptor agonists may be used depending on the patient’s profile.
It’s essential to avoid delay in treatment. Chronic hyperglycemia can damage blood vessels, nerves, kidneys, and eyes—even in the absence of symptoms.
The Future: Continuous Glucose Monitoring (CGM)
Wearable CGM devices, once reserved for type 1 diabetics, are now increasingly used in non-diabetic individuals to optimize metabolic health. They provide real-time glucose data and help users see how meals, sleep, and activity impact glucose trends—including fasting levels.
While CGMs are not necessary for everyone, they can offer unparalleled insights for those struggling with stubborn glucose elevations or experimenting with diet and exercise strategies.
Conclusion
A good fasting glucose number is generally between 75 and 90 mg/dL, with anything below 100 mg/dL considered normal. However, context is key. A value near 99 mg/dL in someone with additional risk factors may warrant early intervention, even if it’s still within the so-called normal range.
Glucose metabolism is influenced by a multitude of factors—diet, hormones, sleep, stress, age, and genetics. Understanding these dynamics empowers both patients and clinicians to make informed decisions that can prevent the onset of diabetes or manage it more effectively.
Monitoring fasting glucose is a powerful, accessible tool. When used wisely and interpreted in context, it becomes a window into one’s metabolic well-being and long-term health.
Related topics:
What Should Blood Sugar Be Before Dinner?
How Frequently Should Diabetics Check Their Blood Sugar?
Why Do Libre 2 Sensors Give Inaccurate Blood Sugar Readings?